If you’ve been struggling with symptoms like hormonal acne, PMS, fatigue, mood swings, or irregular periods, it’s natural to assume your hormones are to blame and they probably are. But what most people don’t realize is that hormones rarely get out of balance on their own. As I often say, hormones are not a root cause. There’s usually something upstream causing the disruption… and the gut is one of the biggest culprits.
Yep. That bloating, constipation, or indigestion you’ve been brushing off? It could be the very thing that’s messing with your hormones.
And here’s the kicker: this applies whether you’re in your 20s dealing with breakouts and period pain, navigating PCOS or birth control recovery… or you’re in your 40s or 50s moving through perimenopause or menopause.
No matter where you are in your hormonal journey, your gut plays a foundational role.
So if you’ve ever wondered why a practitioner like me recommends gut testing when your main complaint is hormonal, here’s your answer.
3 Key Ways Gut Health Impacts Hormones
Your liver breaks down estrogen (and other hormones), and your gut helps move them out of the body into the toilet. Yes, your poop is the primary vehicle that carries used up hormones out of your body. But if your gut isn’t working well due to sluggish digestion, low stomach acid, constipation, or dysbiosis (an imbalance of good and bad microbes)—those “spent” hormones can get reabsorbed into circulation.
This recirculation can lead to symptoms of estrogen dominance like:
You have a subset of gut bacteria called the estrobolome that’s specifically involved in estrogen metabolism. When your gut is in balance, the estrobolome helps maintain healthy estrogen levels. But when there’s dysbiosis, your estrobolome can either increase or decrease estrogen activity inappropriately.
A healthy gut helps you “Goldilocks” your hormones—not too high, not too low.
When the gut lining becomes more permeable (aka “leaky gut”), it allows inflammatory compounds to pass into the bloodstream. This chronic low-grade inflammation can:
So What Can You Do About It?
Start by supporting the basics of gut health:
If symptoms persist—or if you’ve “tried everything” and still feel off—it may be time to do a deeper dive with gut testing, including a stool analysis and food sensitivity test.
The Bottom Line
Your hormones don’t operate in a vacuum. They’re deeply connected to your gut, your liver, your immune system—even your stress levels. So if you’ve been chasing hormonal balance without looking under the hood, it might be time to shift the approach.